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Drug Expiration Dates: Are Expired Drugs Still Safe to Take?

In this article, we'll explore what happens when drugs expire and what you need to know to stay safe.

April 4, 2023

What Happens When Drugs Expire

Have you ever wondered what happens when the expiration date on your prescription medication passes?

Do the drugs become ineffective or even dangerous to consume?

These are common questions that many people have, and for good reason.

Key Takeaways

  • Manufacturers set medication expiration dates, but they don’t always mean that the medication stops working after that date.
  • Some medications can be harmful if taken after their expiration date.
  • Storing your medications according to the instructions their labels can help them stay effective until their expiration date.
  • There are a few different ways to dispose of expired prescriptions and over-the-counter items.
  • The safest way to dispose expired prescriptions is to bring your medications to a drug take-back location.

What Does An Expiration Date Mean?

An expiration date is the last day that a manufacturer guarantees the full potency and safety of a medication. It's important to note that this date doesn't necessarily indicate when a drug will become ineffective or dangerous, but rather serves as a guideline for consumers and healthcare providers.

expired drugs

The expiration date is determined through stability testing conducted by the manufacturer, which assesses how long a drug will remain safe and effective under specific storage conditions. Factors such as temperature, humidity, and exposure to light can all impact a drug's shelf life.

It's also worth noting that different types of medications may have different expiration dates. For example, liquid medications may have shorter shelf lives than solid pills or tablets due to their increased susceptibility to contamination and degradation.

While it's generally recommended to follow the expiration date on a medication, it's also important to use common sense when assessing whether a drug is still safe and effective to consume. If you notice any signs of degradation or if your symptoms persist despite taking medication, be sure to consult with your healthcare provider for advice on whether the medication should be continued or replaced.

How Are Drug Expiration Dates Determined?

Drug expiration dates are determined through a process called stability testing. During stability testing, manufacturers expose their products to a variety of environmental conditions, such as heat, humidity, and light.

By doing so, they can determine how long the drug will remain safe and effective under certain storage conditions.

The results of stability testing help manufacturers determine an appropriate expiration date for their product. This date is typically set based on the time at which the drug is expected to lose 10% of its potency.

For example, if a medication has a shelf life of two years, it may be expected to retain 90% of its potency after that time period.

It's important to note that some drugs may have shorter or longer expiration dates depending on their chemical composition and other factors. Additionally, some medications may require special storage conditions in order to maintain their effectiveness for the full duration of their shelf life.

If you're unsure about how long a medication will remain effective or safe to consume, be sure to consult with your healthcare provider or pharmacist. They can provide guidance on proper storage and disposal methods for your medications and help you make informed decisions about your health and wellness.

The Basics of Drug Expiration Dates

First, it's important to understand what drug expiration dates mean. The expiration date is the last day that the manufacturer guarantees the full potency and safety of the drug. This means that after the expiration date, the drug may not work as well as it should, or it could potentially be harmful to consume.

It's worth noting that drug expiration dates are not set in stone. In fact, many drugs are still effective and safe to consume for years after their expiration date. However, the longer a drug sits on the shelf, the more likely it is to lose potency and become less effective.

How Drugs Degrade Over Time

The degradation of drugs over time is a complex process that varies depending on the drug and its storage conditions. Some drugs break down into harmful substances, while others simply lose their potency. Here are some examples of how different types of drugs degrade over time:

  • Antibiotics: Antibiotics can lose their effectiveness over time, which is why it's important to take the full course of antibiotics prescribed by your doctor. If you have leftover antibiotics from a previous prescription, they may not work as well as they should.
  • Insulin: Insulin can lose its potency over time, which can be dangerous for people with diabetes who rely on it to regulate their blood sugar levels.
  • Nitroglycerin: Nitroglycerin is a medication used to treat chest pain caused by angina. Over time, nitroglycerin can break down into harmful substances, which is why it's important to replace it regularly.
  • Epinephrine: Epinephrine is a medication used to treat severe allergic reactions. Over time, epinephrine can lose its potency, which can be dangerous in an emergency situation.

How to Properly Dispose of Expired Drugs

If you have expired drugs in your medicine cabinet, it's important to dispose of them properly. Flushing them down the toilet or throwing them in the trash can be harmful to the environment and potentially dangerous to others. Here are some safe ways to dispose of expired drugs:

  • Take them to a drug take-back program: Many communities have drug take-back programs where you can safely dispose of expired drugs.
  • Mix them with kitty litter or coffee grounds: Mixing expired drugs with kitty litter or coffee grounds can make them less appealing to animals and people who might accidentally consume them.
  • Follow the instructions on the label: Some drugs come with specific instructions for disposal. Be sure to follow these instructions carefully.

The Difference Between Expiration Dates and Beyond-Use Dates for Drugs

It's important to note that there is a difference between expiration dates and beyond-use dates for drugs. While the expiration date is set by the manufacturer and indicates the last day that the drug will be fully potent and safe, beyond-use dates are determined by pharmacists or healthcare providers.

Beyond-use dates take into account factors such as how the drug will be stored, how it will be administered, and other variables that can impact its effectiveness. For example, a pharmacist may assign a beyond-use date to a medication that has been opened or reconstituted because it may not remain stable for as long as an unopened medication.

It's important to follow both expiration dates and beyond-use dates when taking medications. If you're unsure about whether a medication is still effective or safe to consume, talk to your doctor or pharmacist. They can help you determine whether the drug should be discarded or if it's still suitable for use.

Common Misconceptions About Drug Expiration Dates

Despite the wealth of information available on drug expiration dates, there are still some common misconceptions that persist. Here are a few of the most prevalent myths:

  • Myth #1: All expired drugs are dangerous to consume. As we mentioned earlier, many drugs remain safe and effective for years after their expiration date. However, this doesn't mean you should hold onto your medications indefinitely. It's always best to follow the manufacturer's recommended expiration date or consult with your doctor or pharmacist.
  • Myth #2: Drugs become toxic once they expire. While some drugs can break down into harmful substances over time, this isn't true for all medications. In fact, many simply lose their potency and become less effective.
  • Myth #3: Storing drugs in the freezer can extend their shelf life. While it's true that storing some medications in the freezer can slow down the degradation process, this isn't true for all drugs. In fact, freezing certain medications can actually cause them to break down more quickly.
  • Myth #4: The expiration date is a hard-and-fast rule. While it's generally a good idea to follow drug expiration dates, it's important to remember that they're not set in stone. A medication may still be safe and effective weeks or even months after its printed expiration date.

By understanding these common misconceptions about drug expiration dates, you can make informed decisions about how to manage your medications safely and effectively. If you have any questions or concerns about a specific medication, don't hesitate to talk to your healthcare provider or pharmacist for guidance.

How to Tell if a Drug has Expired or Gone Bad

While many drugs remain safe and effective for years after their expiration date, others may lose their potency or even become harmful to consume. Here are some signs that a drug may have expired or gone bad:

  • Changes in color or texture: If you notice that your medication has changed in color or texture, it may be a sign that it has gone bad. For example, liquid medications may become cloudy or discolored over time, while pills or tablets may appear cracked or discolored.
  • Unpleasant odor: An unpleasant odor can be a sign that your medication has expired or gone bad. If you notice a strange smell coming from your medication, it's best to err on the side of caution and dispose of it properly.
  • Ineffective treatment: If you're taking medication for a specific condition and you're not seeing any improvement in your symptoms, it could be a sign that the drug has lost its potency.

It's worth noting that some drugs may not show any outward signs of expiration or degradation. This is why it's important to always check the expiration date before taking any medication and to consult with your healthcare provider if you have any concerns about its effectiveness.

person holding pink and white medicine pill

In addition to checking for signs of expiration, it's also important to store your medications properly. Most drugs should be stored in a cool, dry place away from direct sunlight and moisture. Be sure to follow the storage instructions provided by the manufacturer and talk to your pharmacist if you have any questions about how best to store your medications.

By keeping an eye out for these signs of expiration and storing your medications properly, you can help ensure that your drugs remain safe and effective for as long as possible.

The Role of the FDA in Regulating Drug Expiration Dates

The Food and Drug Administration (FDA) is responsible for regulating drug expiration dates in the United States. The FDA requires drug manufacturers to conduct stability testing on their products to determine how long they will remain safe and effective. Based on these stability tests, the manufacturer sets an expiration date for the product.

In addition to setting expiration dates, the FDA also regulates how drugs are labeled with respect to their shelf life. For example, the FDA requires that all prescription and over-the-counter medications include an expiration date on their packaging.

The FDA also periodically reviews and updates its guidelines for drug stability testing to ensure that they reflect current scientific knowledge and best practices. These guidelines help ensure that consumers can have confidence in the safety and efficacy of their medications.

It's worth noting that while the FDA plays an important role in regulating drug expiration dates, it's ultimately up to consumers to be vigilant about checking expiration dates and properly disposing of expired medications. By doing so, we can help reduce the risk of taking ineffective or potentially harmful drugs.

The Difference Between Expiration Dates and Beyond-Use Dates for Drugs

It's important to note that there is a difference between expiration dates and beyond-use dates for drugs. While the expiration date is set by the manufacturer and indicates the last day that the drug will be fully potent and safe, beyond-use dates are determined by pharmacists or healthcare providers.

Beyond-use dates take into account factors such as how the drug will be stored, how it will be administered, and other variables that can impact its effectiveness. For example, a pharmacist may assign a beyond-use date to a medication that has been opened or reconstituted because it may not remain stable for as long as an unopened medication.

It's important to follow both expiration dates and beyond-use dates when taking medications. If you're unsure about whether a medication is still effective or safe to consume, talk to your doctor or pharmacist. They can help you determine whether the drug should be discarded or if it's still suitable for use.

What To Do With Expired Medication

Properly disposing of expired medications is crucial to ensure that they don't end up in the wrong hands or pollute our environment. Here are a few additional tips on what to do with expired meds:

  • Don't share your medications: Even if you have leftover medication that hasn't yet expired, it's important not to share it with others. Medications are prescribed for specific conditions and dosages, and taking someone else's medication can be dangerous.
  • Check community drug take-back programs: Many local communities have drug take-back programs where you can safely dispose of expired medications. These programs often work with law enforcement agencies to ensure that medications are disposed of properly and don't end up in the wrong hands.
  • Follow FDA guidelines for disposal: The FDA recommends disposing of most medications by mixing them with an unpalatable substance like kitty litter or coffee grounds, placing them in a sealed container, and throwing them away in the trash. However, some medications may require special disposal methods. Be sure to check with your pharmacist or healthcare provider if you're unsure about how to dispose of a specific medication.

By following these tips and properly disposing of expired medications, we can all do our part to keep ourselves and our communities safe and healthy.

Conclusion

Drug expiration dates are an important consideration when it comes to your health and safety. While many drugs are still effective and safe to consume after their expiration date, it's important to be aware of how different drugs degrade over time.

By properly disposing of expired drugs and following the instructions on your medication, you can help ensure that you're getting the full potency and safety of your prescription medication.

References

  1. https://www.fda.gov/drugs/special-features/dont-be-tempted-use-expired-medicines
  2. https://www.health.harvard.edu/staying-healthy/drug-expiration-dates-do-they-mean-anything
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040264/
  4. https://www.drugs.com/article/drug-expiration-dates.html
  5. https://www.goodrx.com/healthcare-access/medication-education/is-it-dangerous-to-use-expired-medications
Dr. Elizabeth Drew
Medical Director

Medical Director Dr. Elizabeth Drew graduated from Hahnemann University School of Medicine and completed her family practice residency at Lehigh Valley Hospital in Allentown PA. In 2005, she opened her family medicine office in Doylestown, and in 2008 she treated her first patient for opiate addiction.

Since then Dr. Drew has attained her board certification in Addiction Medicine, treated more than a thousand patients for addiction to opiates and alcohol, participated in programs to educate the community, traveled to Washington DC to educate our legislators, and served as Medical Director at some of the best addiction treatment programs in Pennsylvania.

She understands that addiction is a chronic disease that no one would choose to have, and her treatment philosophy is based on respect, compassion, and empowerment. She is excited to be the Medical Director of MPower Wellness and work to provide superior addiction treatment in Chester County.

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