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Is Gabapentin Addictive?

While gabapentin is generally considered safe and effective for these uses, there has been some concern in recent years about whether the drug is addictive.

May 10, 2023

Understanding a Gabapentin Addiction

Gabapentin, also known by the brand names Neurontin and Gralise, is a medication used to treat epilepsy, neuropathic pain, and restless leg syndrome. It is also sometimes prescribed off-label for conditions such as anxiety disorders, migraines, and insomnia.

Pill R 637 Gray Capsule-shape is Gabapentin

Is Gabapentin Addictive?

Yes, Gabapentin can be addictive. Many people use it for legitimate medical conditions, but some people become addicted to the drug and may misuse it.

Frequent use of gabapentin can lead to physical dependence on the drug, which is a normal bodily response when taking a drug regularly.

If you become physical dependent on gabapentin, you will experience a withdrawal syndrome whenever you lower or stop its use.

While gabapentin is not considered to be a controlled substance by the United States Drug Enforcement Administration (DEA), there have been reports of people abusing the drug for recreational purposes.

Some individuals who abuse gabapentin report experiencing a sense of euphoria or a "high" similar to that produced by drugs such as marijuana or opioids.

However, the risk of addiction to gabapentin is relatively low compared to other drugs of abuse.

Unlike opioids, for example, gabapentin does not produce a physical dependence that leads to withdrawal symptoms when the drug is discontinued. Additionally, studies have shown that the drug has a relatively low potential for abuse compared to other substances.

That being said, there are certain factors that may increase the risk of developing an addiction to gabapentin. One such factor is a history of substance abuse or addiction. Individuals who have struggled with addiction in the past may be more likely to abuse gabapentin and develop a dependence on the drug.

Another risk factor is taking gabapentin in higher doses than prescribed or using the drug for longer than recommended. Doing so can increase the likelihood of experiencing side effects such as dizziness, drowsiness, and impaired coordination. These side effects can be dangerous, especially when combined with other substances such as alcohol.

It is also worth noting that gabapentin can interact with other medications and substances, including opioids and benzodiazepines. Combining gabapentin with these drugs can increase the risk of side effects and may lead to overdose or even death.

How Does Gabapentin Work?

Gabapentin works by affecting the activity of certain neurotransmitters in the brain, including gamma-aminobutyric acid (GABA).

GABA is a naturally occurring neurotransmitter that helps to regulate brain activity and is involved in reducing anxiety, promoting relaxation, and inducing sleep.

By increasing the amount of GABA in the brain, gabapentin can help to reduce seizures and relieve neuropathic pain.

However, the exact mechanism by which gabapentin produces these effects is not fully understood and is still being studied.

Gabapentin Uses in Addiction Treatment

Some researchers believe that gabapentin may also affect the release of other neurotransmitters such as glutamate and norepinephrine, which could contribute to its therapeutic effects.

Gabapentin has also been studied for its potential use in addiction treatment.

Some research suggests that the drug may be effective in reducing cravings and withdrawal symptoms associated with alcohol and opioid dependence.

One study found that gabapentin was as effective as benzodiazepines in treating alcohol withdrawal, with fewer side effects. Another study found that gabapentin reduced symptoms of opioid withdrawal and increased the likelihood of completing detoxification treatment.

However, more research is needed to fully understand the role of gabapentin in addiction treatment. It is important to note that gabapentin should only be used under the supervision of a medical professional and as part of a comprehensive treatment plan that includes counseling and behavioral therapies.

Gabapentin Side Effects

Gabapentin is generally considered safe and well-tolerated, but like all medications, it can cause side effects. Some of the most common side effects of gabapentin include dizziness, drowsiness, and fatigue. Other side effects may include:

  • Nausea and vomiting
  • Headache
  • Dry mouth
  • Diarrhea or constipation
  • Blurred vision
  • Difficulty speaking or slurred speech

More serious side effects are rare but can occur. These may include mood changes such as depression or suicidal thoughts, allergic reactions such as hives or difficulty breathing, and swelling of the face, lips, tongue, or throat.

If you experience any unusual symptoms while taking gabapentin, it is important to contact your healthcare provider right away. They can help determine whether the symptoms are related to the medication and advise on appropriate next steps.

Symptoms of Gabapentin Withdrawal

Symptoms of Gabapentin withdrawal can be uncomfortable and may include insomnia, anxiety, sweating, nausea, vomiting, restlessness, and seizures.

The severity and duration of withdrawal symptoms can vary depending on the individual and the dosage of the drug they were taking. It is important to taper off gabapentin use gradually under the supervision of a healthcare provider to minimize the risk of withdrawal symptoms.

If you experience any unusual symptoms while tapering off gabapentin, it is important to contact your healthcare provider right away. They can help determine whether the symptoms are related to the medication and advise on appropriate next steps.

Symptoms of Gabapentin Overdose

Symptoms of gabapentin overdose can be serious and require immediate medical attention. Some common symptoms of an overdose include difficulty breathing, extreme drowsiness, blurred vision, slurred speech, and loss of consciousness. In severe cases, an overdose can lead to coma or death.

You must seek emergency medical care if you suspect that you or someone else has taken too much gabapentin.

Additionally, it is important to keep track of your medication and take it only as prescribed by your healthcare provider to minimize the risk of an overdose.

Why Is Gabapentin Addictive?

Gabapentin can be addictive for a few reasons. For one, the drug can cause feelings of relaxation and euphoria in some users, which can create a psychological dependence on the drug.

Additionally, gabapentin is often used to manage chronic pain, anxiety, and other conditions that can last for extended periods.

This means that patients may take the drug for long periods, sometimes even years, which increases the likelihood of developing a physical dependence on it.

Finally, some people may abuse gabapentin as a way to enhance the effects of other drugs such as opioids or benzodiazepines.

When taken in combination with these substances, gabapentin can increase their potency and produce more intense effects.


Q: Can I become addicted to gabapentin if I use it as prescribed?

A: While the risk of addiction to gabapentin is relatively low, it is still possible to become addicted even when using the drug as prescribed. It's important to follow your healthcare provider's instructions carefully and notify them if you experience any unusual symptoms or side effects.

Q: How do I know if I am becoming addicted to gabapentin?

A: Signs of gabapentin addiction may include taking higher doses than prescribed, experiencing cravings for the drug, and continuing to use the drug despite negative consequences such as impaired functioning or relationship problems. It's important to seek help from a healthcare provider or addiction specialist if you think you might be struggling with addiction.

Q: Can I stop taking gabapentin on my own?

A: If you have been taking gabapentin for an extended period of time, it is important to taper off the drug gradually under the supervision of a healthcare provider to minimize the risk of withdrawal symptoms. Attempting to stop taking gabapentin abruptly can lead to uncomfortable and potentially dangerous withdrawal symptoms.

Q: What should I do if someone I know is struggling with gabapentin addiction?

A: If you suspect that someone you know is struggling with gabapentin addiction, it's important to encourage them to seek help from a healthcare provider or addiction specialist. You can also provide emotional support and offer resources such as helplines or support groups.

Q: Are there any alternative medications that can be used instead of gabapentin?

A: Depending on the condition being treated, there may be alternative medications or therapies that can be used instead of or in combination with gabapentin. It's important to discuss all treatment options with your healthcare provider and work together to develop a comprehensive treatment plan that meets your individual needs.


In conclusion, while gabapentin is not considered to be highly addictive, there is some potential for abuse and dependence. Individuals who have a history of substance abuse or who are taking the drug in higher doses than prescribed should be monitored closely for signs of addiction.

It is important to speak with a healthcare provider before starting or stopping any medication, including gabapentin, and to follow the prescribed dosages and instructions carefully.


  1. https://americanaddictioncenters.org/addiction-medications/gabapentin
  2. https://www.addictioncenter.com/drugs/gabapentin/
  3. https://www.drugs.com/medical-answers/gabapentin-addictive-3573085/
  4. https://www.statnews.com/2017/07/06/gabapentin-becomes-target-of-opioid-abuse/
Dr. Elizabeth Drew
Medical Director

Medical Director Dr. Elizabeth Drew graduated from Hahnemann University School of Medicine and completed her family practice residency at Lehigh Valley Hospital in Allentown PA. In 2005, she opened her family medicine office in Doylestown, and in 2008 she treated her first patient for opiate addiction.

Since then Dr. Drew has attained her board certification in Addiction Medicine, treated more than a thousand patients for addiction to opiates and alcohol, participated in programs to educate the community, traveled to Washington DC to educate our legislators, and served as Medical Director at some of the best addiction treatment programs in Pennsylvania.

She understands that addiction is a chronic disease that no one would choose to have, and her treatment philosophy is based on respect, compassion, and empowerment. She is excited to be the Medical Director of MPower Wellness and work to provide superior addiction treatment in Chester County.

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